We consider an SIR endemic model in which the Skin Care contact transmission function is related to the number of infected population.By theoretical analysis, it is shown that the model exhibits the bistability and undergoes saddle-node bifurcation, the Hopf bifurcation, and the Bogdanov-Takens bifurcation.Furthermore, we find that the threshold va
PEGylation technology, that is grafting of poly(ethylene glycol)(PEG) to biologics, vaccines and nanopharmaceuticals, has become a cornerstone of modern medicines with over thirty products used in the clinic.PEGylation of therapeutic proteins, nucleic acids and nanopharmaceuticals improves their stability, pharmacokinetic and biodistribution.While
Abstract Background In Papua New Guinea (PNG) members of key populations, including female sex workers (FSW), men who have sex with men (MSM) and transgender women (TGW), have higher rates of HIV compared to the general adult population and Horn Knot low engagement in HIV care.This paper examines the socio-ecological factors that encourage or hinde